Plain-English translation of NCT07437729 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This research study is investigating why chronic kidney disease damages the tiny blood vessels in your body. Specifically, researchers want to understand a protective layer inside blood vessels called the glycocalyx and how oxidative stress (a type of cellular damage) affects it. The study will compare how blood vessels work in three groups: people with kidney disease from high blood pressure, people with high blood pressure but healthy kidneys, and healthy volunteers.
People with chronic kidney disease often have problems with their small blood vessels that get worse over time, but doctors don't fully understand why this happens. This study aims to identify the specific mechanisms causing this damage so that better treatments can be developed in the future.
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You will visit the research clinic for testing. Researchers will measure how your small blood vessels respond to stimuli using a laser blood flow meter and check the thickness of the protective layer inside your blood vessels. You will also have blood drawn so scientists can measure markers of inflammation and cellular damage. The study is observational, meaning you are not taking any new medications — researchers are simply studying how your body works compared to the other groups.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
Croatia
Sponsor
Josip Juraj Strossmayer University of Osijek
Enrollment target
~105 participants
Started
October 2025
Primary completion
September 2029
Age range
18 Years and older
Last updated on clinicaltrials.gov in March 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Ines Drenjančević, MD, PhD
Faculty of Medicine Josip Juraj Strossmayer University of Osijek
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.