Plain-English translation of NCT07438652 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study compares two different eating patterns—the Mediterranean diet (rich in vegetables, fruits, and olive oil) and the Paleolithic diet (emphasizing lean meats, fish, and vegetables while avoiding grains and processed foods)—to see if either one can reduce joint inflammation and improve how you feel if you have rheumatoid arthritis. You'll follow one of these diets for 12 weeks, or continue eating normally if you're in the control group, while researchers measure changes in your disease activity, muscle strength, and overall quality of life.
Rheumatoid arthritis causes ongoing inflammation and damage to joints, and many patients struggle with pain, fatigue, and reduced quality of life even with current medications. Recent research suggests that what you eat may help calm inflammation and improve symptoms, but doctors need solid proof to recommend specific diets alongside standard treatment.
You likely qualify if…
You likely don't qualify if…
You'll be randomly assigned to one of three groups: the Mediterranean diet, the Paleolithic diet, or a control group where you eat as you normally do. Over 12 weeks, you'll follow your assigned diet while visiting the clinic for check-ins that include blood tests, measurements of your weight and waist size, and questionnaires about your fatigue, sleep, stress, and how you're feeling overall. Researchers will compare how your joint inflammation and quality of life change across the three groups.
AI-generated summary from trial data · Jun 5, 2026 · Not medical advice
Egypt