Plain-English translation of NCT07439939 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This research explores how blood clotting behavior changes in patients with liver cirrhosis when they undergo a procedure called a transjugular intrahepatic portosystemic shunt (TIPS) — a minimally invasive way to reduce dangerous pressure buildup in the liver. Researchers want to understand why patients with cirrhosis are at risk for blood clots in the portal vein (the major blood vessel that carries blood to the liver), and how the procedure affects clotting balance.
Patients with advanced liver disease often develop unwanted blood clots in their portal vein, but doctors don't fully understand why this happens. This study aims to clarify whether changes in the liver's blood vessels, immune response, and clotting factors work together to cause these dangerous clots.
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If you enroll, you will have blood samples collected as part of your scheduled TIPS procedure — no extra visits are needed beyond your regular medical care. The researchers will analyze these samples to study how your blood's clotting factors change during and after the procedure. Your participation helps doctors understand the blood clotting risks in cirrhosis patients.
AI-generated summary from trial data · Jun 12, 2026 · Not medical advice
France
Enrollment target
~45 participants
Started
March 2026
Primary completion
June 2027
Age range
18 Years and older
Last updated on clinicaltrials.gov in April 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Stéphanie ROULLET stephanie.roullet@aphp.fr, PhD
Assistance Publique - Hôpitaux de Paris
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.