Plain-English translation of NCT07442851 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Sickle Cell Disease research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing a program called SickleFit that combines personalized exercise training with support from a nutrition expert. The study is designed for adults age 35 and older who have sickle cell disease, and it aims to see whether this combination approach can help improve how well you function day-to-day and your overall quality of life.
Many adults living with sickle cell disease experience fatigue, pain, and reduced physical ability as they age, which can make daily activities harder. This trial exists to test whether exercise and better nutrition can help improve strength, stamina, and quality of life for this group.
You likely qualify if…
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If you join the SickleFit group, you'll complete a fitness and function assessment, then participate in 12 weeks of personalized exercise sessions and nutrition guidance from a dietitian, with another assessment at the end. If you're in the control group, you'll continue your usual care for 12 weeks while on a waiting list, complete the same assessments, and then have the option to do the SickleFit program afterward.
AI-generated summary from trial data · Jun 6, 2026 · Not medical advice
United States
Sponsor
Duke University
Enrollment target
~40 participants
Started
April 2026
Primary completion
January 2028
Age range
35 Years and older
Last updated on clinicaltrials.gov in May 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Teagan Callaway
Duke University
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.