Plain-English translation of NCT07443696 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial is testing a new heart imaging scan called XTR003 that works together with another standard imaging technique to help doctors see which parts of your heart are still healthy and might recover after surgery. Researchers want to know if this new combined imaging approach can better predict which patients with severe heart failure from blocked arteries will improve after their heart vessels are opened back up.
Many patients with severe heart damage from poor blood flow are unsure whether surgery to restore blood flow will actually help them. This medication aims to give doctors a clearer picture of which heart tissue can still be saved, so they can make better treatment decisions and help more patients.
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You will be randomly assigned to one of two groups — one will receive the imaging scan while fasting, and the other will receive glucose (sugar) before the scan. Both groups will undergo heart imaging scans (PET scans and heart ultrasounds) before and after your scheduled heart surgery, as well as an MRI scan of your heart. You'll return for follow-up visits over 6 months to check for any complications and to see how well your heart has improved after surgery.
AI-generated summary from trial data · Jun 11, 2026 · Not medical advice
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