Plain-English translation of NCT07446478 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing Temporal Interference Stimulation (TIS), a new type of non-invasive brain stimulation that uses electrical fields to reach deep structures in the brain. Researchers believe this treatment may help improve thinking skills, memory, and daily functioning in people with schizophrenia by helping different brain regions communicate better. You would receive this stimulation twice daily for 10 days.
People with schizophrenia often struggle with thinking, memory, and attention problems that regular medications don't fully address. This trial exists to see whether this new brain stimulation approach can help with these cognitive challenges by targeting specific areas deep in the brain.
You would visit the research clinic for 10 days, receiving the brain stimulation treatment twice each day. Before and after the treatment period, you would complete thinking and memory tests, answer questions about how you're functioning, and have brain imaging scans. The stimulation itself is non-invasive—electrodes are placed on your scalp—and the entire process takes about 2–3 weeks from start to finish.
AI-generated summary from trial data · Aug 6, 2026 · Not medical advice
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