Plain-English translation of NCT07454070 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study is testing transcutaneous auricular vagus nerve stimulation (taVNS)—a non-invasive treatment that uses gentle electrical pulses on your ear to help ease depression. Many people develop depression after having a stent placed to open blocked heart arteries, and this trial explores whether this ear-based treatment could help reduce those feelings without the side effects of antidepressant medications.
After heart stent procedures, depression affects many patients and makes it harder to follow medical advice and recover well. While antidepressant pills can help, they don't work for everyone, take several weeks to kick in, and often cause unwanted side effects. This study is exploring this treatment as a potentially faster and safer option.
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You would visit the clinic weekly for 8 weeks. Twice each day, you would use a small device that delivers gentle electrical stimulation to your ear for 20 minutes per session. Half of participants will receive the active treatment, and half will receive a sham (placebo) version—neither you nor the research staff will know which one you're getting. The team will check in with you regularly to track your mood and make sure the treatment is safe.
AI-generated summary from trial data · Jul 7, 2026 · Not medical advice
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