Plain-English translation of NCT07457060 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 4 — The treatment has already been approved. Researchers are tracking how it works in a large number of people over time.
This trial is testing different ways to give polio vaccines to babies around 2 months old. Researchers want to compare four different vaccination schedules using inactivated poliovirus vaccine to find out which combination provides the best protection and causes the fewest side effects. The study will follow 480 healthy infants and measure how well their bodies respond to the vaccine.
Polio is a serious disease that can cause paralysis, and vaccination is the best way to prevent it. Researchers want to find the most effective and safest way to give these vaccines to very young infants, which could improve protection for babies around the world.
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Your infant will receive three doses of polio vaccine spaced 28 days apart. Each dose will be given either as a muscle injection or under the skin (your group will be randomly assigned). You'll watch for immediate reactions for 30 minutes after each dose, then use a diary card to track any side effects for 28 days after each vaccination. Your infant will have blood drawn before the first vaccine and again 28 days after the last dose to check how well the body responded.
AI-generated summary from trial data · Oct 12, 2026 · Not medical advice
Philippines