Plain-English translation of NCT07460531 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Heart Failure research guide →SOPHIE is a long-term observational study that enrolls 2,000 people with heart failure to understand the relationship between physical activity and heart health outcomes. Researchers will ask you about your activity level using questionnaires and ask you to wear a pedometer or activity tracker to measure your daily steps. The study will then follow you for ongoing check-ins to see how your activity relates to your heart health, hospitalizations, and overall well-being.
While exercise is often recommended for heart failure patients, doctors want to understand more clearly how different levels of physical activity actually affect real-world health outcomes like hospital visits and quality of life. This study will help doctors give better personalized advice about activity for people living with heart failure.
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At the start, you'll complete questionnaires about your physical activity and wear a pedometer or activity tracker to measure your daily steps for a week. Every six months after that, the research team will call you to ask about your activity level again and check in on your health — whether you've had any heart-related hospital visits, changes in your symptoms, or other health events. The study continues for several years, but your involvement mainly involves these periodic phone calls and wearing your activity tracker.
AI-generated summary from trial data · Jun 19, 2026 · Not medical advice
Germany
Italy
Sponsor
LMU Klinikum
Enrollment target
~2,000 participants
Started
February 2025
Primary completion
December 2030
Age range
18 Years and older
Last updated on clinicaltrials.gov in March 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Stefan Brunner, MD
LMU Klinikum
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.