Plain-English translation of NCT07460960 on ClinicalTrials.gov โ ยท Source last updated ยท Translation generated ยท How we translate trials
Phase 2 โ Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This study is testing two cholesterol-lowering medications โ pitavastatin and rosuvastatin โ to see how they affect testosterone levels and erectile function in middle-aged men at high risk for heart disease. Researchers want to understand whether these medications, which are commonly used to protect the heart, have any negative effects on male sexual health. The hope is that by improving blood vessel health, these medications may actually improve erectile function rather than harm it.
Cholesterol-lowering medications are very important for preventing heart attacks and strokes, but some men worry that they might affect their sexual function or testosterone levels. This trial exists to directly test whether this medication is safe for male sexual health, so doctors and patients can make informed treatment decisions without unnecessary fear.
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You will be randomly assigned to take one of two cholesterol-lowering medications daily for 6 months. You'll have check-in visits at 1, 3, and 6 months where doctors will assess your erectile function through questionnaires, measure your testosterone and other hormones with blood tests, and evaluate how well your blood vessels are working. The study takes place at a research center in Moscow over 9 months of recruitment, with each participant involved for 6 months of active monitoring.
AI-generated summary from trial data ยท Jun 22, 2026 ยท Not medical advice
Russia