Plain-English translation of NCT07462013 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
The POWER study is testing whether a fish oil supplement called Eicosapentaenoic Acid (EPA) can help reduce depression symptoms and protect memory in adults over 50 who have major depressive disorder. Many people with depression also experience memory problems and difficulty thinking clearly. This study wants to find out if taking this medication daily might help prevent or slow down these cognitive changes.
People with depression often struggle with memory loss and thinking problems that can seriously affect their quality of life. Researchers want to explore whether this medication—combined with lifestyle approaches like exercise and healthy eating—could be an effective way to prevent these thinking problems from developing or getting worse.
You likely qualify if…
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If you enroll, you will be randomly assigned to take either the fish oil supplement or a placebo (a dummy pill that looks identical) every day for the duration of the study. You'll attend regular clinic visits where researchers will assess your depression symptoms, memory, and thinking abilities using standard tests. The study also incorporates lifestyle support around physical activity, cognitive training, and diet to support your overall brain health.
AI-generated summary from trial data · Jun 22, 2026 · Not medical advice
Taiwan
Sponsor
National Science and Technology Council, Taiwan
Collaborators
IRCCS Centro San Giovanni di Dio Fatebenefratelli, University College Cork
Enrollment target
~120 participants
Started
October 2025
Primary completion
June 2028
Age range
50 Years – 80 Years
Last updated on clinicaltrials.gov in June 2026.
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.