Plain-English translation of NCT07463183 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial is testing a new medication called as a treatment for moderate to severe ulcerative colitis. The medication is given as an injection under the skin, and researchers want to see if it can help more people reach remission—meaning their UC symptoms go away or become much milder—compared to a placebo (a dummy injection). The study will follow participants for about a year to see how well the medication works and if it's safe.
Many people with ulcerative colitis don't respond well enough to current treatments or stop responding over time. This trial exists to find out if this new medication could be a better option for people whose UC is still moderate to severe despite existing treatments.
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Over the course of about a year, you would receive injections of either the new medication or a placebo once a week for the first 12 weeks. If your symptoms don't improve, you would then receive the actual medication for another 12 weeks. If you do respond well, you would continue getting the medication for several more months. Throughout the study, you would have regular clinic visits and blood tests to see how the treatment is working and to monitor for any side effects.
AI-generated summary from trial data · Jul 20, 2026 · Not medical advice
United States