Plain-English translation of NCT07463625 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Cushing's disease is caused by a small tumor in the pituitary gland that produces too much of a hormone called ACTH. Standard MRI scans miss about 30% of these tiny tumors. This study is testing whether a newer type of scan called [18F]FET PET can find these tumors more reliably and help surgeons plan better treatment.
Currently, when MRI doesn't clearly show where the tumor is, doctors sometimes have to do invasive procedures to find it. This trial exists to see if the new scan can find these tumors more accurately, potentially helping patients avoid those extra procedures and improving surgical outcomes.
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You would have already had standard MRI imaging as part of your regular care. For this study, you would receive a specialized PET scan using a radioactive tracer to see if it better identifies your tumor. If you proceed with surgery, the researchers will compare what the scan showed to what surgeons actually find during the operation. You may also have blood tests checked to see how the scan findings match your hormone levels.
AI-generated summary from trial data · Jun 4, 2026 · Not medical advice
France
Enrollment target
~20 participants
Started
November 2023
Primary completion
November 2027
Age range
18 Years and older
Last updated on clinicaltrials.gov in March 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Anthime FLAUS, MD
Hospices Civils de Lyon
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.