Plain-English translation of NCT07464756 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial is testing whether , a newer type of immunotherapy medication, combined with chemotherapy can help shrink advanced stomach cancers before surgery. Half of participants will also receive a second medication called that helps block blood vessel growth in tumors. The goal is to see if these medications work better than chemotherapy alone in preparing the tumor for surgical removal.
Advanced stomach cancers are difficult to treat, and surgery alone doesn't always prevent the cancer from returning. Researchers want to see if giving patients new medications before surgery can shrink the tumor more effectively and improve long-term survival chances.
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You will be randomly assigned to one of two groups: one receiving the new medication plus chemotherapy, or another group receiving , , and chemotherapy. You will take these medications before surgery—the exact schedule will be explained by your study team. During treatment, you will have regular clinic visits for blood tests, imaging scans, and check-ups to monitor how well the treatment is working and watch for side effects. After you complete the medication phase, you will proceed to surgery as planned.
AI-generated summary from trial data · Aug 5, 2026 · Not medical advice
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