Plain-English translation of NCT07465796 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This is one of the first times this treatment has been tested in people.
This is a first-in-human study of the CIPHER System, a new flexible device with many tiny electrodes that can be placed on the brain surface during tumor removal surgery. The device records electrical activity in the brain to help surgeons understand which areas are important to protect. In this early study, researchers want to learn if the device is safe and works well during brain surgery for newly diagnosed gliomas (a type of brain tumor).
Current tools for mapping the brain during tumor surgery use rigid probes with limited electrode coverage, which can miss important information about healthy brain function. This new treatment offers a more flexible and detailed way to map brain activity, which could help surgeons remove more tumor while protecting vital brain tissue and potentially improve patient outcomes.
You likely qualify if…
You likely don't qualify if…
If you join this study, the CIPHER device will be placed on your brain surface during your scheduled tumor removal surgery. Depending on which group you're assigned to, the device will either only record your brain's electrical activity, or it will both record activity and deliver gentle electrical stimulation. The device is used only during the surgery itself, and the study is designed to be short-term, focusing on whether the device is safe and works as intended during this single procedure.
AI-generated summary from trial data · Jun 10, 2026 · Not medical advice
Australia