Plain-English translation of NCT07468383 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study is testing a new procedure called cardioneuroablation that uses a catheter (a thin tube) to treat a slow heartbeat by targeting overactive nerve clusters in the heart. Instead of implanting a permanent pacemaker device, this procedure aims to reset abnormal nerve signaling that causes the heart to beat too slowly. Researchers want to understand whether this approach is safe and effective for people whose slow heartbeat is caused by an overactive vagus nerve.
Many patients with a slow heartbeat caused by nerve problems face limited options—either living with uncomfortable symptoms like fainting and dizziness, or undergoing surgery to implant a permanent pacemaker device. Preliminary studies suggest this new treatment could offer relief without permanent implants, but doctors need larger, more rigorous studies to confirm it really works and is safe.
You likely qualify if…
You likely don't qualify if…
If you qualify, you will be randomly assigned to either receive the cardioneuroablation procedure or a sham procedure (a procedure without the actual ablation, used for comparison). The study combines laboratory research with clinical visits to carefully evaluate whether the treatment improves your symptoms, increases your resting heart rate, and is safe over time. You can expect multiple follow-up appointments to monitor your heart rhythm and symptoms.
AI-generated summary from trial data · Jul 4, 2026 · Not medical advice
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