Comparing two surgical systems for cataract removal

Plain-English translation of NCT07468877 on ClinicalTrials.gov ↗ · Source last updated March 2026 · Translation generated October 2026 · How we translate trials

This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.

What is this trial?

This trial is testing whether the Unity VCS/CS surgical system works better than the Centurion system when removing cataracts from your eyes. Both are ultrasound-based machines that your surgeon uses to break up and remove the cloudy lens during cataract surgery. The study will measure how much energy each system uses and how long the procedure takes.

Cataract surgery is very common, but doctors want to find ways to make it safer and more efficient by using less energy during the procedure. This trial will help surgeons understand which system might be gentler on the eye while still effectively removing the cataract.

Do you qualify?

You likely qualify if…

you are 18 years old or older
you have been diagnosed with cataracts in both eyes that are moderate to advanced in severity
you need cataract surgery with lens implants in both eyes and are willing to have them done one after the other
you are healthy enough to undergo surgery and can give your informed consent
your cataracts are not complicated by other eye conditions or prior eye surgery

You likely don't qualify if…

you have had eye surgery in the past 3 months or prior eye surgery that might affect the results
you have weak or damaged eye structures that would require special support devices during surgery
you have a history of eye inflammation, retinal problems, or corneal disease
you need special pupil-expanding devices or laser-assisted cataract removal
your cataract is extremely dense or dark, which could interfere with measuring the study results

What participation looks like

You would have cataract surgery on both eyes performed by the same surgeon. One eye would be treated with the Unity system and the other with the Centurion system (randomly assigned). Your surgeon would measure how much ultrasound energy each system used and how long each surgery took. You would likely have follow-up visits after surgery to ensure your eyes are healing well, though specific visit timing is not detailed in this trial summary.

AI-generated summary from trial data · Oct 12, 2026 · Not medical advice

Trial locations(1 site)

United States

Advanced Vision Care, Los Angeles, California