Plain-English translation of NCT07469267 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Breast Cancer research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial compares two different radiation therapy approaches for women with early-stage breast cancer who had small cancer deposits (called macro-metastases) in their sentinel lymph nodes. One group receives targeted radiation to the lower armpit lymph nodes only, while the other group receives broader radiation to multiple lymph node areas. The trial is testing whether the more focused approach works just as well while potentially causing fewer side effects.
Radiation therapy after breast cancer surgery helps prevent cancer from coming back, but doctors aren't sure whether treating a smaller, focused area is just as effective as treating a larger region. This trial will help guide future treatment decisions and potentially reduce unnecessary radiation exposure.
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After you've had breast surgery, you will be randomly assigned to receive one of two radiation approaches. You'll receive radiation to your breast or chest wall, and one group will get focused treatment of the lower lymph nodes while the other receives broader treatment of multiple lymph node areas. Radiation typically occurs over several weeks, and you'll have follow-up visits to monitor your health and any side effects for years afterward.
AI-generated summary from trial data · Jun 18, 2026 · Not medical advice
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