Plain-English translation of NCT07470879 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial is testing a medication called to see if it can help children with moderately to severely active ulcerative colitis—a condition where the colon becomes inflamed and causes pain, bleeding, and diarrhea. Researchers want to learn whether this medication is safe and effective for children, and how the body processes it. If a child completes the initial 52 weeks of treatment, they may have the option to continue the medication for up to 4 additional years to see how well it works long-term.
While there are some medicines available for ulcerative colitis in children, doctors need more options that are proven safe and work well in younger patients. This trial tests whether this medication could become another helpful choice for families dealing with this painful disease.
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Your child would take the medication by mouth once each day for up to 52 weeks. During this time, your child will have regular study visits where doctors will check how the medication is working, monitor for any side effects, and take blood samples to understand how the body processes the medication. If your child does well and you both wish to continue, you would have the opportunity to keep giving the medication for several more years as part of a long-term follow-up program.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
Canada
Germany
Japan