Plain-English translation of NCT07478809 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This is a retrospective study — meaning researchers will look back at medical records from patients who already participated in an earlier trial called RATIONALE-307. The study is collecting long-term survival data from patients with advanced squamous non-small cell lung cancer who received tislelizumab (an immunotherapy medication) combined with chemotherapy as their first treatment. The goal is to understand how well this medication works over the long term and to identify which patients benefit the most.
While earlier results from the RATIONALE-307 trial showed promise, researchers want to gather more information about how patients do over many years of follow-up. This longer-term data will help doctors better understand which patients are most likely to have lasting benefit from this treatment approach.
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Since this is a retrospective study, you would not need to visit a clinic or take any new medication. Instead, researchers would review your existing medical records from the RATIONALE-307 trial to collect information about how long you have survived and how you have responded to treatment over time. Your participation mainly involves allowing researchers access to your stored health information.
AI-generated summary from trial data · Jul 18, 2026 · Not medical advice
China
Sponsor
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Enrollment target
~109 participants
Started
February 2026
Primary completion
December 2026
Last updated on clinicaltrials.gov in March 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Zhijie Wang, MD
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.