Plain-English translation of NCT07482566 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing two different surgical approaches for treating advanced cancer that forms at the junction where your stomach meets your esophagus. One approach removes only the upper part of your stomach (proximal gastrectomy), while the other removes the entire stomach (total gastrectomy). Researchers want to compare which surgery is safer, has fewer complications, and works better at controlling the cancer long-term.
Traditionally, removing the entire stomach has been the standard approach for this type of cancer, but newer evidence suggests that removing only part of the stomach might help patients recover better and have fewer side effects. This trial will provide clear evidence to help doctors decide which surgery is the best choice for future patients.
You likely qualify if…
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If you join this trial, you will be randomly assigned to receive one of two surgical approaches—either removal of just the upper part of your stomach or removal of your entire stomach. Your surgery will be performed by an experienced surgeon using whichever technique (open surgery, laparoscopic, or robotic) is best for you. After surgery, you will have follow-up visits over the next five years, during which doctors will check how you're recovering, monitor for any side effects, and track whether the cancer returns.
AI-generated summary from trial data · Jun 7, 2026 · Not medical advice
Turkey (Türkiye)