Ozone Gas Therapy for Mouth Sores From Cancer Treatment

This trial is testing gas ozone therapy to treat oral mucositis—painful sores and ulcers that develop in the mouth during chemotherapy or radiation for cancer. Researchers want to see if ozone gas, applied directly to affected areas in a clinic setting, can reduce pain and help the mouth heal. They're also testing whether adding a special home oral care routine (a mouthwash and toothpaste) works even better than ozone therapy alone.

Mouth sores from cancer treatment are common and can be severe enough to interfere with eating, swallowing, and even completing cancer therapy on schedule. Right now, there is no proven standard treatment that consistently reduces these sores, so researchers are investigating whether this treatment approach can provide real relief and improve quality of life.