Surgery combined with heated chemotherapy for pancreatic cancer spread to abdomen

This trial is testing a combined approach for pancreatic cancer that has spread to the lining of your abdomen. The treatment involves surgery to remove your pancreatic tumor and visible cancer spots in your belly, followed by heated chemotherapy (Cisplatin and Paclitaxel) delivered directly into the abdominal cavity during the operation. The goal is to learn whether this intensive combination approach is safe, manageable, and improves how long patients survive.

Pancreatic cancer that spreads to the abdominal lining is very difficult to treat with standard chemotherapy alone. This trial exists to find out whether adding heated chemotherapy during surgery—which delivers the medication directly where the cancer is—might help people live longer and have better outcomes than current treatments.