Plain-English translation of NCT07493447 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1 — Testing in a small group (usually 20–80 people) to find a safe dose and watch for side effects.
This trial is testing , a special fluorescent dye that may help surgeons see brain tumors more clearly during surgery. You would receive one injection of this medication 1–5 days before your scheduled brain surgery. The dye glows under special surgical lights, which could help your surgeon identify and remove more of the tumor while protecting healthy brain tissue.
Brain tumors can be difficult for surgeons to see completely during surgery because tumor tissue can look similar to normal brain tissue. This medication may help surgeons distinguish tumor from healthy brain by making the tumor glow, potentially improving surgery outcomes and reducing the need for additional procedures.
You likely qualify if…
You likely don't qualify if…
You would receive one injection of the fluorescent dye medication 1–5 days before your scheduled brain surgery. You would be monitored immediately after the injection for any side effects. During your surgery, your surgeon would use special imaging equipment to see the fluorescent dye highlighting the tumor. After surgery, you would have blood draws and follow-up visits with the study team through Day 15 to check for any side effects, while continuing your normal post-surgical care with your doctors.
AI-generated summary from trial data · Jul 6, 2026 · Not medical advice
United States
Phase
Safety & dosing
Sponsor
Eben Rosenthal
Enrollment target
~30 participants
Started
July 2026
Primary completion
May 2030
Age range
18 Years and older
Last updated on clinicaltrials.gov in June 2026.
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Central contact
Makenna Brown
Vanderbilt University Medical Center
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