Plain-English translation of NCT07500012 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This pilot study is testing a non-invasive device called transcutaneous auricular vagus nerve stimulation (taVNS) that gently stimulates a nerve in your ear to help manage pain and other symptoms common in breast cancer survivors. Researchers want to see if using this device at home twice daily for four weeks can safely and effectively reduce pain, anxiety, depression, and fatigue. The study will also look at how the treatment affects your gut health and brain activity.
Many breast cancer survivors struggle with ongoing pain, anxiety, depression, and fatigue even after completing their cancer treatment. This medication offers a potential drug-free option that patients can use at home, and early research suggests it may help by activating the vagus nerve, which plays an important role in managing stress and inflammation.
You likely qualify if…
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If you join this study, you will be randomly assigned to receive either the active ear stimulation device or a sham (inactive) device. You'll use your assigned device at home twice daily for 30 minutes each session, over a 4-week period, for a total of 56 sessions. You'll also provide stool samples at certain times and undergo non-invasive brain imaging scans to help researchers understand how the treatment works. The study team will check in with you regularly to monitor how you're doing.
AI-generated summary from trial data · Jun 6, 2026 · Not medical advice
United States
Sponsor
Florida State University
Enrollment target
~40 participants
Started
February 2026
Primary completion
December 2027
Age range
18 Years – 79 Years
Sex
Female only
Last updated on clinicaltrials.gov in March 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Jie Chen
Florida State University
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.