Exercise Training to Strengthen Muscles and Lungs in Children With Cystic Fibrosis

This trial is testing whether structured exercise training—using specially designed arm and leg cycling machines—can help children with cystic fibrosis build stronger muscles, improve their heart and lung capacity, and strengthen their breathing. Children in the study will do either upper body exercises (using an arm cycle) or lower body exercises (using a leg cycle) two to three times per week. Researchers want to see if this regular training helps reduce some of the physical challenges that come with cystic fibrosis.

Children with cystic fibrosis often develop weak muscles and reduced lung function because thick mucus damages their airways and the disease causes ongoing inflammation and low energy. This study exists to find out whether regular, guided exercise can help build strength and improve breathing—potentially helping children with cystic fibrosis do more activities and feel better day-to-day.