Plain-English translation of NCT07509450 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This pilot study is testing fecal microbiota transplantation—a procedure where healthy gut bacteria from a donor are transferred into your intestines—in patients receiving CAR-T cell therapy or stem cell transplants for blood cancers. Researchers believe that restoring healthy gut bacteria may help your body tolerate these intensive cancer treatments better and reduce complications.
Intensive cancer treatments like CAR-T therapy and stem cell transplants can damage the healthy bacteria in your gut, which plays an important role in your immune system and overall health. This trial is exploring whether this treatment could protect that bacteria and help your body recover better.
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You would receive a fecal microbiota transplant before your cancer cell therapy begins, and then again about 30 days after treatment. Throughout the study, you'll have blood tests, provide stool and urine samples, and complete questionnaires about how you're tolerating the procedure. The total study lasts about 2.5 years, with at least 6 months of follow-up visits after your initial cancer treatment.
AI-generated summary from trial data · Jul 16, 2026 · Not medical advice
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