Recruiting

Personalized Weight Loss Program for Heart Disease Patients

Plain-English translation of NCT07514611 on ClinicalTrials.gov ↗ · Source last updated May 2026 · Translation generated August 2026 · How we translate trials

This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.

What is this trial?

This study is testing whether a personalized weight loss program can help people with coronary heart disease (a condition where blood vessels to the heart are narrowed) who are also overweight or obese. Half of the participants will receive routine care only, while the other half will use a smartphone app that creates a customized meal plan and exercise program based on their individual health needs, with weekly check-ins using a smart scale.

Weight loss is known to improve heart health, but many patients struggle to lose weight safely on their own. This trial aims to see whether personalized guidance using technology and professional support from cardiologists and nutritionists can help people with heart disease achieve meaningful weight loss.

Do you qualify?

You likely qualify if…

you are between 18 and 65 years old
you have been diagnosed with coronary heart disease confirmed by imaging or a prior heart attack
your body mass index (BMI) is 28 or higher, indicating you are overweight or obese
you genuinely want to lose weight and are motivated to try
you own a smartphone and are comfortable using it
you can perform daily activities independently

You likely don't qualify if…

you have had unstable chest pain or a heart attack in the past month
you have liver or kidney disease, or are on dialysis
you have severe lung disease, severe arthritis, or other conditions that prevent you from exercising safely
you have a severe mental health condition, eating disorder, or cognitive problems that would affect your diet
you are pregnant, breastfeeding, or unwilling to use contraception if you could become pregnant

What participation looks like

If you are selected for the weight loss group, you will first meet with a cardiologist, dietitian, and exercise specialist who will assess your fitness level and create a personalized plan for you. Over six months, you will use a smartphone app that tracks your meals and suggests exercises matched to your fitness level, weigh yourself each morning on a provided smart scale that automatically uploads your weight, and aim to lose about 0.5 kg per week in the first month, then 2% of your body weight each month after that. If you are in the routine care group, you will only receive standard diet and exercise advice for heart disease patients and no special app or monitoring.

AI-generated summary from trial data · Aug 12, 2026 · Not medical advice

Trial locations(1 site)

China

Guangdong Provincial People's Hospital, Guangzhou, Guangdong