Plain-English translation of NCT07519876 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study is investigating whether people who have a heart opening—a condition that 1 in 4 people are born with and never know about—face a higher risk of stroke after experiencing a pulmonary embolism (a blood clot in the lungs). Researchers will compare stroke outcomes between people with this heart opening and those without it by using brain imaging and heart ultrasound tests.
When a small hole exists in the heart, a blood clot can sometimes pass through it and travel to the brain, causing a stroke. Doctors don't yet know if people with lung blood clots and this heart condition face greater stroke danger, so this study is designed to answer that important question.
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You would participate for about 90 days. During this time, you'll have your medical records reviewed, undergo a brain MRI scan and a heart ultrasound test (using sound waves and a special saline injection) to check for a heart opening, and then return for a follow-up visit 90 days later for a second brain MRI and additional assessments. The study is observational, meaning researchers are watching and comparing outcomes rather than giving you any new treatment.
AI-generated summary from trial data · Jun 7, 2026 · Not medical advice
United States
Collaborators
Occlutech International AB
Enrollment target
~256 participants
Started
January 2026
Primary completion
February 2026
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years and older
Last updated on clinicaltrials.gov in April 2026.
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