A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma — Stella
Phase 3 — Large-scale testing across thousands of people, comparing the new treatment against current standard treatments.
(212 sites) United States
Investigative Site US058, Birmingham, Alabama Investigative Site US016, Anchorage, Alaska Investigative Site US026, Chandler, Arizona Investigative Site US045, Tucson, Arizona Investigative Site US051, Duarte, California Investigative Site US048, Fountain Valley, California Investigative Site US049, Irvine, California Investigative Site US054, La Jolla, California Investigative Site US027, Los Angeles, California Investigative Site US036, Los Angeles, California Investigative Site US019, Los Angeles, California Investigative Site US034, San Francisco, California Investigative Site US001, Santa Monica, California Investigative Site US071, Denver, Colorado Investigative Site US013, Washington D.C., District of Columbia Investigative Site US046, Washington D.C., District of Columbia Investigative Site US072, Fort Myers, Florida Investigative Site US075, Miami, Florida Investigative Site US073, West Palm Beach, Florida Investigative Site US074, Winter Park, Florida Investigative Site US023, Atlanta, Georgia Investigative Site US079, Chicago, Illinois Investigative Site US030, Evanston, Illinois Investigative Site US005, Naperville, Illinois Investigative Site US009, Springfield, Illinois Investigative Site US021, Indianapolis, Indiana Investigative Site US007, New Orleans, Louisiana Investigative Site US022, Boston, Massachusetts Investigative Site US006, Ann Arbor, Michigan Investigative Site US010, Detroit, Michigan Investigative Site US078, Grand Rapids, Michigan Investigative Site US012, Ypsilanti, Michigan Investigative Site US066, Maple Grove, Minnesota Investigative Site US047, Hattiesburg, Mississippi Investigative Site US077, Hackensack, New Jersey Investigative Site US017, Morristown, New Jersey Investigative Site US059, Lake Success, New York Investigative Site US031, New York, New York Investigative Site US041, New York, New York Investigative Site US004, New York, New York Investigative Site US003, New York, New York Investigative Site US029, The Bronx, New York Investigative Site US035, Chapel Hill, North Carolina Investigative Site US050, Cleveland, Ohio Investigative Site US020, Cleveland, Ohio Investigative Site US033, Columbus, Ohio Investigative Site US042, Portland, Oregon Investigative Site US008, Philadelphia, Pennsylvania Investigative Site US043, Philadelphia, Pennsylvania Investigative Site US056, Pittsburgh, Pennsylvania Investigative Site US055, Sioux Falls, South Dakota Investigative Site US039, Nashville, Tennessee Investigative Site US060, Nashville, Tennessee Investigative Site US070, Nashville, Tennessee Investigative Site US067, Dallas, Texas Investigative Site US062, Denison, Texas Investigative Site US011, Houston, Texas Investigative Site US018, Houston, Texas Investigative Site US063, San Antonio, Texas Investigative Site US053, Salt Lake City, Utah Investigative Site US076, Charlottesville, Virginia Investigative Site US057, Fairfax, Virginia Investigative Site US065, Fairfax, Virginia Investigative Site US064, Salem, Virginia Investigative Site US032, Seattle, Washington Investigative Site US044, Madison, Wisconsin Australia
Investigative Site AU007, Liverpool, New South Wales Investigative Site AU003, Wollongong, New South Wales Investigative Site AU006, Woodville South, South Australia Investigative Site AU005, Box Hill, Victoria Investigative Site AU004, Melbourne, Victoria Investigative Site AU001, Melbourne, Victoria Investigative Site AU002, Canberra Investigative Site AU008, Perth Austria
Investigative Site AT002, Innsbruck Investigative Site AT004, Linz Investigative Site AT003, Salzburg Investigative Site AT001, Vienna Belgium
Investigative Site BE008, Anderlecht Investigative Site BE003, Brussels Investigative Site BE009, Brussels Investigative Site BE001, Edegem Investigative Site BE005, Ghent Investigative Site BE007, Gilly Investigative Site BE004, Leuven Investigative Site BE006, Liège Investigative Site BE002, Yvoir Canada
Investigative Site CA001, Toronto, Ontario Investigative Site CA005, Laval, Quebec Investigative Site CA006, Montreal, Quebec Investigative Site CA004, Québec, Quebec Denmark
Investigative Site DK006, Aalborg Investigative Site DK005, Århus N Investigative Site DK001, Herlev Investigative Site DK004, Odense C Investigative Site DK003, Roskilde Investigative Site DK002, Vejle Finland
Investigative Site FI001, Helsinki Investigative Site FI003, Tampere Investigative Site FI002, Turku France
Investigative Site FR013, Brest Investigative Site FR012, Chambray-lès-Tours Investigative Site FR014, Dijon Investigative Site FR002, Lille Investigative Site FR011, Lyon Investigative Site FR016, Lyon Investigative Site FR006, Marseille Investigative Site FR015, Montpellier Investigative Site FR003, Paris Investigative Site FR009, Paris Investigative Site FR004, Pessac Investigative Site FR008, Poitiers Investigative Site FR010, Reims Investigative Site FR005, Rennes
Germany
Investigative Site DE018, Berlin Investigative Site DE020, Berlin Investigative Site DE003, Bochum Investigative Site DE019, Bonn Investigative Site DE008, Cologne Investigative Site DE001, Dresden Investigative Site DE013, Düsseldorf Investigative Site DE004, Essen Investigative Site DE005, Frankfurt Investigative Site DE016, Freiburg im Breisgau Investigative Site DE017, Göttingen Investigative Site DE002, Halle Investigative Site DE007, Hamburg Investigative Site DE006, Hamburg
Italy
Investigative Site IT002, Bologna Investigative Site IT010, Brescia Investigative Site IT009, Candiolo Investigative Site IT012, Foggia Investigative Site IT006, Milan Investigative Site IT008, Milan Investigative Site IT011, Naples Investigative Site IT003, Pisa Investigative Site IT004, Roma Investigative Site IT005, Rome Investigative Site IT001, Rozzano Investigative Site IT007, Verona Japan
Investigative Site JP002, Kashiwa-shi Investigative Site JP003, Kōtoku Investigative Site JP007, Mitaka-shi Investigative Site JP004, Osaka Investigative Site JP006, Toyama Investigative Site JP001, Yokohama Netherlands
Investigative Site NL001, Amsterdam Investigative Site NL007, Eindhoven Investigative Site NL005, Groningen Investigative Site NL003, Maastricht Investigative Site NL006, Nieuwegein Norway
Investigative Site NO002, Bergen Investigative Site NO001, Oslo Investigative Site NO005, Stavanger Investigative Site NO003, Trondheim Poland
Investigative Site PL008, Gdansk Investigative Site PL003, Krakow Investigative Site PL007, Warsaw Investigative Site PL002, Warsaw Investigative Site PL001, Warsaw Investigative Site PL004, Wroclaw Puerto Rico
Investigative Site PR001, Dorado South Korea
Investigative Site KR004, Goyang-si Investigative Site KR005, Seongnam Investigative Site KR007, Seongnam-si Investigative Site KR002, Seoul Investigative Site KR006, Seoul Investigative Site KR001, Seoul Investigative Site KR003, Seoul Investigative Site KR008, Seoul Spain
Investigative Site ES011, Badalona Investigative Site ES003, Barcelona Investigative Site ES002, Barcelona Investigative Site ES014, Las Palmas de Gran Canaria Investigative Site ES016, Madrid Investigative Site ES006, Madrid Investigative Site ES007, Madrid Investigative Site ES012, Madrid Investigative Site ES008, Madrid Investigative Site ES013, Madrid Investigative Site ES005, Palma de Mallorca Investigative Site ES009, Santander Investigative Site ES010, Seville Investigative Site ES015, Valencia
Sweden
Investigative Site SE003, Linköping Investigative Site SE001, Malmo Investigative Site SE002, Solna Switzerland
Investigative Site CH005, Basel Investigative Site CH003, Bern Investigative Site CH004, Geneva Investigative Site CH002, Lausanne Investigative Site CH001, Zurich United Kingdom
Investigative Site GB008, Dundee Investigative Site GB011, Guildford Investigative Site GB002, Headington Investigative Site GB001, Leeds Investigative Site GB009, London Investigative Site GB004, London Investigative Site GB003, Manchester Investigative Site GB006, Metropolitan Borough of Wirral Investigative Site GB010, Northwood Investigative Site GB005, Norwich
Key details Sponsor
Incyte Corporation
Enrollment target
~588 participants
Primary completion
September 2028
Age range
18 Years and older
Last updated April 2026
Interested in joining? Investigative Site FR007, Toulouse
Investigative Site FR001, Villejuif Investigative Site DE009, Leipzig
Investigative Site DE015, Munich Investigative Site DE014, München Investigative Site DE010, Nuremberg Investigative Site DE011, Ulm Investigative Site ES017, Valencia
Investigative Site ES001, Valencia Investigative Site ES004, Zaragoza