Plain-English translation of NCT07524322 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Breast Cancer research guide →Phase 1 — Testing in a small group (usually 20–80 people) to find a safe dose and watch for side effects.
This is one of the first times this treatment has been tested in people.
This trial is testing a new oral medication called in people with advanced cancers that have spread and contain a specific mutation in the PIK3CA gene. The study will evaluate how safe the medication is, how your body processes it, and whether it can help shrink or slow down your cancer. Researchers want to find the right dose and see if this treatment works for people whose cancers haven't responded to standard therapies.
Many advanced cancers have mutations in the PIK3CA gene that help them grow. Existing treatments don't work well for all of these patients, so researchers developed this medication to target this specific genetic change and offer a new treatment option.
You likely qualify if…
You likely don't qualify if…
You would take the medication by mouth at home, following the dosing schedule your study team provides. You would visit the clinic regularly for safety monitoring, blood tests, and imaging scans to see how your cancer is responding. The study has two phases: first, researchers test increasing doses to find the safest and most effective level, then they expand to focus on breast cancer patients. Throughout participation, your study team will closely watch for any side effects and adjust your treatment as needed.
AI-generated summary from trial data · Jul 7, 2026 · Not medical advice
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