Testing an antibiotic to improve recovery after stroke treatment

This study is testing whether a medication called minocycline can improve recovery in people who have had an acute ischemic stroke and are receiving emergency clot-busting therapy. Minocycline is an antibiotic that has been shown in earlier research to protect brain cells from damage after a stroke. The trial will compare this medication to a placebo (a pill with no active ingredient) to see if it truly helps people regain more function and independence in the 90 days after their stroke.

While emergency clot-busting treatment is standard care for stroke, many patients still experience serious disability afterward. Research suggests that this medication may work alongside standard stroke therapy to reduce inflammation in the brain and prevent additional damage, potentially helping more people recover better.