Recruiting

How stress affects pancreatic cancer outcomes after surgery

Plain-English translation of NCT07529626 on ClinicalTrials.gov ↗ · Source last updated June 2026 · Translation generated July 2026 · How we translate trials

What is this trial?

This research is studying whether chronic stress—including anxiety, depression, and sleep trouble—plays a role in how pancreatic cancer progresses after surgery. Researchers will ask you about your emotional well-being and sleep quality at several points during your treatment, and they'll track your cancer outcomes over time to see if stress levels are connected to how your disease develops.

Pancreatic cancer is a serious illness, and doctors know that stress and mental health can affect physical health outcomes. This study exists to understand whether managing psychological stress could help improve survival and recovery in pancreatic cancer patients.

Do you qualify?

You likely qualify if…

you are 18 years old or older
you have been diagnosed with pancreatic cancer confirmed by biopsy or tissue sample
you are able to read, write, or communicate well enough to complete questionnaires—either on your own, with help from research staff, or with family support
you are willing to sign a consent form and participate in the study

You likely don't qualify if…

you have severe memory problems, dementia, or serious confusion that prevents you from completing assessments and you have no family member to help
you have another severe, uncontrolled medical condition (like heart, lung, or kidney failure) with a life expectancy of less than 3 months
you are unable to understand Chinese or have severe vision or hearing loss that prevents you from completing questionnaires and you have no family member to help
you have a known serious psychiatric disorder that would prevent you from participating

What participation looks like

You will complete several short questionnaires about your mood, anxiety, and sleep quality at the start and then at key moments during your cancer treatment—such as mid-way through chemotherapy, at the end of treatment, and during follow-up visits. Researchers will also collect a small blood sample (2 mL) during routine blood work and gather information from your medical records about your cancer stage and treatment. You'll be contacted every 3 months for about a year or longer to provide updates on your health status and any changes in your condition.

AI-generated summary from trial data · Jul 3, 2026 · Not medical advice

Trial locations(3 sites)

China

the Third Xiangya Hospital of Central South University, Changsha, Hunan

Zhongshan Hospital Affiliated to Fudan University, Shanghai, Shanghai Municipality

The First Affiliated Hospital of Xi'an Jiao Tong University, Xi’an, Shanxi