Plain-English translation of NCT07534462 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study is watching how a device called Impella 5.5—a temporary mechanical heart pump—affects how both sides of your heart work when you have end-stage heart failure. Researchers will use heart ultrasounds to measure your heart's strength and function before the device is placed, right after it starts working, and for up to two weeks afterward. This is an observational study, meaning the doctors are simply watching and measuring; they're not changing your regular treatment plan.
Doctors know this mechanical pump can help very sick hearts, but they want to better understand exactly how it changes the way both sides of the heart function. This information could help them use this treatment more effectively for patients like you in the future.
You likely qualify if…
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You will have heart ultrasounds (echocardiograms) at three time points: before your Impella device is placed, right after it starts working during your procedure, and during the first two weeks after surgery. The research team will also look at routine measurements like your blood pressure and oxygen levels that are already being monitored as part of your regular care. All of this happens alongside your normal treatment—nothing about the study changes how your doctors care for you.
AI-generated summary from trial data · Sep 17, 2026 · Not medical advice
United States
Collaborators
Johnson & Johnson
Enrollment target
~24 participants
Started
July 2026
Primary completion
July 2027
Age range
18 Years and older
Last updated on clinicaltrials.gov in September 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
YOSHIHISA MORITA
University of Rochester
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.