Plain-English translation of NCT07535008 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether professional dental cleaning can help prevent chronic graft-versus-host disease (GVHD), a serious complication that can happen after a blood stem cell transplant. In this study, patients receive a thorough dental cleaning before their transplant begins and another simplified cleaning 28 days after their transplant. Researchers want to see if keeping teeth and gums healthy can reduce the risk of developing GVHD.
Graft-versus-host disease happens when cells from a donor's immune system attack a patient's own tissues after transplant, and it can cause long-lasting problems. Recent research suggests that infections in the mouth and gums might trigger or worsen this complication, so this trial is exploring whether preventive dental care can lower that risk.
You likely qualify if…
You likely don't qualify if…
If you qualify, you will receive a thorough dental cleaning before your transplant begins (if you haven't had one in the past 3 months). Then, 28 days after your transplant, you will receive a simplified dental cleaning at the clinic. After that, you will have follow-up visits at day 84, day 180, and 1 year after your transplant, where your mouth health and overall recovery will be monitored. The entire study lasts about one year.
AI-generated summary from trial data · Jun 22, 2026 · Not medical advice
United States