Plain-English translation of NCT07537699 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial is testing whether ear acupressure (a traditional Chinese medicine technique using seeds taped to specific points on your ear) combined with dexamethasone (a steroid medication) can help prevent nausea and vomiting caused by chemotherapy. The chemotherapy being used—docetaxel combined with cyclophosphamide—is a common treatment for breast cancer after surgery, but it often causes severe nausea that can be hard to manage with standard anti-nausea drugs alone.
While strong anti-nausea medications work, they can cause their own problems like constipation, loss of appetite, and bloating that hurt patients' quality of life and make them less likely to complete treatment. This trial explores whether adding ear acupressure to a lower dose of the steroid medication might prevent nausea just as well but with fewer side effects.
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Before each chemotherapy session, Vaccaria seeds (small seeds used in traditional Chinese medicine) will be taped to specific points on your ear, and you'll apply gentle pressure to them until you feel mild soreness. You'll keep the seeds on your ear from the day of chemotherapy through day 5. You'll also receive dexamethasone, a steroid medication, to help prevent nausea. The trial will track how well this combination works at preventing nausea and vomiting over the 5 days following your chemotherapy.
AI-generated summary from trial data · Jun 30, 2026 · Not medical advice
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