Plain-English translation of NCT07539766 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This research study is following 250 people with obesity who are planning to have weight loss surgery. The goal is to understand how common a specific type of heart problem (preserved ejection fraction heart failure) is in people with obesity, and whether weight loss surgery and lifestyle changes can prevent or improve it. Researchers will check participants' heart health, fitness, and quality of life before surgery and again at 1 and 2 years after surgery.
Obesity and heart problems are connected, but doctors don't fully understand how common heart-related problems are in people with obesity or how weight loss surgery affects the heart. This study aims to fill that gap so doctors can better prevent heart disease in people seeking weight loss surgery.
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You would have detailed heart and health assessments at the obesity clinic before your weight loss surgery, including heart tests, fitness tests (like a 6-minute walking test), blood work, and quality-of-life questionnaires. After your surgery and lifestyle treatment program, you would return for similar assessments at 1 year and 2 years after surgery. The study follows you over two years to see how your heart health changes as you lose weight.
AI-generated summary from trial data · Jun 5, 2026 · Not medical advice
Netherlands