Finding the Best Sickle Cell Medicine Dose for Nigerian Patients

This research study is looking at how hydroxyurea — a medication commonly used to treat sickle cell disease — works differently in people of Nigerian descent. Researchers want to understand why some patients respond better to this medication than others, and they're collecting blood samples and health information to build a personalized treatment plan that could help doctors find the right dose for each patient.

Many sickle cell patients don't get the full benefit from this medication because doctors don't have a good way to know what dose works best for each person. This study exists to fill that gap by understanding genetic and other factors that affect how the medication works in the body, so treatment can be customized instead of one-size-fits-all.