Plain-English translation of NCT07543562 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Heart Failure research guide →Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
This trial is testing whether selenium, a mineral your body needs, can help people with heart failure live better lives and reduce hospital visits. Researchers believe that some heart failure patients may have low selenium levels, which could make their condition worse. This study will give half of the participants selenium 200 micrograms daily and the other half a placebo (inactive pill) to see if the medication makes a difference.
Despite good heart medications, many people with heart failure still need to go to the hospital and face serious complications. Early research suggests that selenium might help the heart work better and reduce these problems, but doctors need a large, careful study to know for sure.
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You will be randomly assigned to take either selenium or a placebo pill daily, in addition to your regular heart failure medications. The study uses existing heart failure registries in Sweden and Norway to track your health through hospital records and follow-up over time, so you won't need frequent clinic visits. Researchers will monitor you for hospitalizations, quality of life, and other health outcomes to see if the medication helps.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
Norway
Sweden