Plain-English translation of NCT07545694 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Bladder Cancer research guide →Researchers are studying how the body's natural endocannabinoid system (which is also affected by cannabis) controls bladder muscle function. This study uses small samples of bladder tissue removed during cancer surgery to test whether drugs that interact with this system could help control overactive bladder problems. The goal is to understand whether modulating this system might lead to better treatments for bladder control issues.
Most research on how the endocannabinoid system affects the bladder has been done in animals, and results in human tissue have been limited and sometimes contradictory. A clearer understanding of how this system works in human bladders could unlock new treatment options for conditions like overactive bladder syndrome.
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If you qualify, your participation involves donating a small sample of bladder tissue that is removed during your already-scheduled cancer surgery—no additional surgery is needed. The tissue sample is then sent to the laboratory where researchers expose it to different compounds related to the endocannabinoid system and measure how the bladder muscle responds. Your main responsibility is giving informed consent; the actual research happens in the lab.
AI-generated summary from trial data · Jun 10, 2026 · Not medical advice
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