Plain-English translation of NCT07546097 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 4 — The treatment has already been approved. Researchers are tracking how it works in a large number of people over time.
This trial compares two treatment approaches for acute severe ulcerative colitis: a new medication called taken as a daily pill, and corticosteroids (the current standard treatment). Researchers want to see whether the medication works as well as steroids at bringing the disease under control, and whether it causes any side effects.
Corticosteroids have been the standard first-line treatment for severe ulcerative colitis flares for decades, but they can cause significant side effects over time. This trial explores whether this newer medication could be a safer, equally effective alternative for controlling severe flares.
You likely qualify if…
You likely don't qualify if…
You will take either the new medication or corticosteroids daily for 3 months, with the steroid dose tapering down over time. You'll visit the clinic every 2 weeks for blood tests, ultrasounds, and colonoscopies to check how well the treatment is working. You'll also keep track of your bowel movements and any symptoms like abdominal pain at home.
AI-generated summary from trial data · Jun 18, 2026 · Not medical advice
China