Plain-English translation of NCT07549373 on ClinicalTrials.gov ↗ ·
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether a 940nm diode laser, combined with natural substances like apple cider vinegar or gymnema sylvestre (an herbal plant), can more effectively kill bacteria during root canal treatment in people with type 2 diabetes. Root canals are procedures to clean out infected tooth pulp, and this study wants to see if these new methods work better than standard salt water irrigation. The researchers will compare these treatments against the traditional saline approach to see which one best controls the bacteria that cause tooth infections.
People with diabetes often have weaker immune systems and are more prone to serious tooth infections. Existing root canal treatments may not work as well for diabetic patients, so researchers are exploring whether the laser and plant-based treatments might provide better infection control and improve outcomes.
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If you enroll, you'll receive root canal treatment at the university dental clinic over approximately one year. Your infected tooth will be cleaned and treated using one of six different methods: standard salt water, a 940nm laser alone, apple cider vinegar, gymnema sylvestre, or combinations of the laser with one of the natural substances. Before and after treatment, the dentist will take samples to test how well each method kills the bacteria. You'll be assigned randomly to one treatment group, and the entire process follows standard root canal procedures with careful attention to keeping everything sterile.
AI-generated summary from trial data · Jun 4, 2026 · Not medical advice
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