Eye Injection Safety and Heart Health Blood Work Study

Researchers want to understand whether bevacizumab, a medication injected into the eye to treat diabetic vision loss, retinal vein blockage, and age-related macular degeneration, might affect your heart and blood vessel health over time. The study will measure specific enzymes and blood fats in people who have received multiple eye injections and compare them to healthy people who haven't had this treatment. This will help doctors understand whether the medication is safe for your cardiovascular system when used repeatedly.

When this medication is used systemically (throughout the whole body) for cancer treatment, it can raise the risk of blood clots and bleeding. Although the eye injections deliver much smaller doses, patients receive them repeatedly over months or years. Doctors need to know whether these repeated injections might slowly affect heart health and blood vessel function, so they can make the safest treatment decisions.