Testing a new anti-inflammatory medication alongside stroke clot removal

This trial is testing whether a medication called sivelestat sodium can improve recovery when given together with endovascular thrombectomy—a procedure that removes blood clots from the brain during a stroke. The medication is designed to reduce harmful inflammation that happens after the clot is removed, which may help prevent a problem called 'futile recanalization,' where the clot is cleared but the brain still doesn't recover well.

Even when doctors successfully remove a stroke clot, many patients still don't recover as well as hoped because inflammation and additional clot formation damage the brain's tiny blood vessels. This medication works by blocking a substance that causes this post-stroke inflammation, so researchers want to find out if adding it to standard clot-removal treatment can help more patients have better outcomes.