Plain-English translation of NCT07554833 on ClinicalTrials.gov ↗ ·
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This pilot study is testing a treatment called repetitive transcranial magnetic stimulation (rTMS) — a non-invasive procedure that uses magnetic pulses to stimulate the brain — to see if it can help improve both movement symptoms and thinking skills in people with Parkinson's disease. The study uses an accelerated schedule, meaning you receive 6 sessions over just 3 weeks instead of the longer schedules used in previous research. Researchers want to understand how this treatment affects motor function, cognition, mood, and quality of life over a 3-month follow-up period.
While current Parkinson's medications help with movement symptoms, they become less effective over time and can cause unwanted side effects. Previous research suggests rTMS may help, but most studies have required weeks of daily sessions, which is difficult for patients to access and complete. This trial tests a faster schedule to see if it's both effective and more practical.
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You will come to the San Francisco Neurology and Sleep Center twice a week for about 3 weeks to receive the brain stimulation treatment — 6 sessions total. Each session involves placing a magnetic coil on your scalp to deliver pulses to the motor cortex (the part of the brain that controls movement). Before, during, and after treatment, you'll complete assessments of your movement, thinking skills, mood, and quality of life through tests, questionnaires, and physical exams. You'll have follow-up visits at 1 month and 3 months after your last treatment session. The entire study takes about 5 months from start to finish, and you'll need to keep taking your regular Parkinson's medications throughout.
AI-generated summary from trial data · Jun 19, 2026 · Not medical advice
United States