Plain-English translation of NCT07558733 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1/2 — A combined trial that checks safety and dosing while also starting to look at whether the treatment works.
This study is testing a combination of two new medications called and (together called PIKTOR), given alongside an established hormone therapy called . The trial is designed to find the right dose of this medication combination and to see how well it works for people with advanced breast cancer that is hormone-responsive but not HER2-positive.
Many patients with this type of breast cancer eventually stop responding to standard hormone treatments. Researchers believe this medication combination may help by targeting specific pathways in cancer cells that are resistant to traditional therapy, offering a new option for people who need more effective treatments.
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You would take two oral medications by mouth daily and receive an injection of into your muscle on a regular schedule. The study involves multiple clinic visits to monitor your health, check for side effects, and measure how well the treatment is working using scans and blood tests. The trial is still recruiting participants, so the exact length of your involvement would be discussed with the research team based on how you respond to treatment.
AI-generated summary from trial data · Jul 5, 2026 · Not medical advice
United States