Plain-English translation of NCT07559084 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing a new form of brain stimulation called transcranial magnetic stimulation (TMS) to treat the negative symptoms of schizophrenia — such as reduced emotional expression, motivation, and social engagement. Unlike antipsychotic medications, which work well for other schizophrenia symptoms, TMS targets specific brain regions that may help reduce these difficult negative symptoms. The study uses magnetic pulses delivered to three carefully chosen areas of the brain, guided by MRI imaging to ensure precision.
Current antipsychotic medications are effective for some schizophrenia symptoms but offer limited relief for negative symptoms and cognitive difficulties. This trial exists because doctors need better treatment options for these challenging symptoms, and early research suggests that magnetic brain stimulation targeting multiple brain regions may offer a new approach.
If you enroll, you will receive 50 sessions of magnetic brain stimulation over 10 working days (5 sessions per day, with breaks between them). A brain MRI will guide doctors to target three specific brain regions with magnetic pulses. Before and after the treatment period, you will have clinical assessments, cognitive tests, and additional brain imaging to measure whether the treatment helps your symptoms. Your psychiatric medications will remain stable throughout the study.
AI-generated summary from trial data · Jun 11, 2026 · Not medical advice
China
Sponsor
Shanghai Mental Health Center
Enrollment target
~64 participants
Started
October 2026
Primary completion
December 2027
Age range
16 Years – 45 Years
Last updated on clinicaltrials.gov in September 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Huiru Cui, Ph.D
Shanghai Mental Health Center
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.