Plain-English translation of NCT07559877 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
This study is testing whether a topical chlorhexidine spray can help prevent or reduce severe skin damage that sometimes occurs during radiation therapy for nasopharyngeal cancer. Radiation therapy is an effective treatment for this type of cancer, but it can cause painful skin reactions in the treatment area. Researchers want to see if spraying this medication on your skin during and after treatment can protect you from these side effects.
Many patients receiving radiation therapy for throat cancer experience painful, severe skin damage as a side effect of treatment. This trial aims to find out whether this medication can prevent or reduce that damage, helping patients tolerate their cancer treatment more comfortably.
You likely qualify if…
You likely don't qualify if…
If you join this trial, you will spray either the test medication or a placebo (sterile water that looks identical) once daily on your skin after showering, starting the day before radiation therapy and continuing for one week after your treatment ends. You'll spray it evenly over the area being radiated from a distance of 15–20 cm, plus receive standard skin care instructions. The study will track how your skin responds and how the treatment affects your quality of life during your cancer therapy.
AI-generated summary from trial data · Sep 5, 2026 · Not medical advice
China
Phase
Large-scale testing
Sponsor
Jiangxi Provincial Cancer Hospital
Enrollment target
~148 participants
Started
April 2026
Primary completion
June 2027
Age range
18 Years – 75 Years
Last updated on clinicaltrials.gov in April 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Tianzhu Lu, PhD
Jiangxi Provincial Cancer Hospital
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.