Plain-English translation of NCT07562503 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
After surgery for advanced colorectal cancer, this trial is testing whether patients benefit from receiving FOLFOX, CAPOX, FOLFIRI, or CAPIRI chemotherapy for 6 months instead of the standard 3 months. Doctors will also monitor your blood with special tests that detect cancer cells to help decide if you need the extended treatment.
Some patients with advanced colorectal cancer have cancer cells remaining after surgery, even when it's not visible on scans. This study aims to figure out whether giving longer chemotherapy treatment, guided by blood tests that show if cancer cells are still present, can help prevent the cancer from coming back.
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You will be randomly assigned to receive either 3 months of chemotherapy or 6 months of chemotherapy (given as either longer doublet therapy or two different drug combinations for 3 months each). You will have small blood draws (about 1-2 tablespoons) at 1 month, 3 months, and 6 months after your surgery so doctors can monitor cancer cells in your blood. The study lasts about 6 months of active treatment, plus follow-up visits.
AI-generated summary from trial data · Aug 14, 2026 · Not medical advice
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