Recruiting

How hair loss scalp tissue changes with common hair regrowth treatment

Plain-English translation of NCT07563036 on ClinicalTrials.gov ↗ · Source last updated May 2026 · Translation generated August 2026 · How we translate trials

This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.

What is this trial?

This research is looking at how minoxidil — a well-known topical treatment for pattern hair loss — affects a specific protein in the scalp called JAK2. Researchers will take tiny skin samples from your scalp before you start the medication and again after three months of use to measure changes in this protein and see if those changes connect to visible hair regrowth.

While this medication is already widely used and helps many people regrow hair, scientists don't fully understand exactly how it works at the cellular level. This study aims to unlock that understanding so doctors may eventually develop better treatments for hair loss in the future.

Do you qualify?

You likely qualify if…

you are a man aged 18 to 50 years old
you have been diagnosed with pattern hair loss (androgenetic alopecia) that is mild to moderate
you have not received treatment for hair loss in the past month, or you are willing to stop your current hair loss treatments and wait one month before enrolling
you are willing to provide written informed consent and commit to the study visits

You likely don't qualify if…

you have other types of hair loss, such as scarring alopecia or hair loss caused by inflammation
you have inflammatory scalp conditions like psoriasis or dandruff
you are currently taking or have taken JAK inhibitors, immune-suppressing drugs, or systemic steroids in the past 12 months
you have a serious medical history involving kidney, heart, or liver disease
you have bleeding disorders or have received chemotherapy in the past five years

What participation looks like

You will visit the clinic for a baseline appointment where you'll have your scalp photographed and examined, and doctors will take two small skin samples (each about the size of a pencil tip) — one from an area losing hair and one from an area with healthy hair. You'll then apply the topical medication twice daily (men) or once daily (women) for three months. At the end of three months, you'll return for a final visit where one more small skin sample will be taken from the previously balding area to measure changes in the scalp tissue.

AI-generated summary from trial data · Aug 24, 2026 · Not medical advice

Trial locations(1 site)

Egypt

Kasr El Aini Hospital, Cairo, Cairo Governorate